About

NURTuRE (the National Unified Renal Translational Research Enterprise) is the first and unique kidney biobank for chronic kidney disease (CKD) and nephrotic syndrome (NS), covering England, Scotland and Wales.

Biological samples (plasma, serum, urine, DNA and tissue) from 3,000 patients with chronic kidney disease (CKD) and over 800 patients with nephrotic syndrome (NS) from 14 NHS Trusts are being collected and stored* under strict Standard Operating Procedures for both academic and industrial research worldwide. This repository also has the considerable advantage of  containing anonymised linked clinical data, through the UK Renal Registry, which will enable us to develop new biomarkers. This will then lead to a greater ability to identify patients who will benefit from better, earlier diagnosis and person-specific new treatments, leading to better health outcomes.

The development of NURTuRE as a national kidney biobank was one of the recommendations in the UK Renal Research Strategy 2016 (Strategic Aim 1, Recommendation 3) which states:

“Create a national Kidney Biobank for collection and storage of biological samples from every kidney patient, to provide a strategic resource for fundamental and translational research.”

NURTuRE is a research collaboration involving a charity, academia and industry, under the strategic oversight and management of Kidney Research UK. The project is being jointly delivered through the University of Bristol, led by Professor Moin Saleem, Professor of Paediatric Renal Medicine, supported by Liz Colby as co-ordinator for the NURTuRE-NS study; and the University of Nottingham, led by Professor Maarten Taal, Professor of Medicine, supported by Fiona Robertson, co-ordinator of the NURTuRE-CKD study.

From L to R: Liz Colby, Moin Saleem, Fiona Robertson, Maarten Taal

The biobank is funded by AbbVie Inc, Evotec, UCB and Kidney Research UK.

The NURTuRE collaborators will have access to the samples and associated data when they are available.

From mid-2018, other investigators and pharmaceutical companies will be able to apply to an
independent access committee to use stored biosamples and data for future studies. If this is of interest to you, please contact: nurturebiobank@kidneyresearchuk.org in the first instance with details of your request.

For general information about the NURTuRE biobank please contact: nurturebiobank@kidneyresearchuk.org or see the ‘Contacts’ page.

If you are patient interested in getting involved, see the ‘Patients’ page.

 

* Biofluid samples are stored at the UK National Biobank in Milton Keynes and biopsy material at the Clinical Research Facility (CRF) at the Queen Elizabeth Hospital, Birmingham. Biomarker analysis will take place at the University of Geneva and histopathological (tissue) analysis at the University of Birmingham.